Towards reconstruction of gene networks from expression data by supervised learning

Table 2 Classification rules

Gene name	'Simultaneous' rules	Supporting information	'Time delay' and 'changes' rules	Supporting information
SWI5	-CLB1⇔-SWI5	[19]	-	-
	-CLB2⇔-SWI5	[33]
CLN1	+CLN2⇔+CLN1	[22]	-	-
	-CDC20⇔+CLN1
CLN2	-CLB2⇔+CLN2	[20]	±CLB1⇒ CLN2	[20]
	+SWI5⇔-CLN2	[18]		[18]
CLB1	± CLB2⇔±CLB1	[19]	+CLB6⇒-CLB1	[19]
			↑↓ CLB2⇔↑↓ CLB1	[21]
CLB2	-CLB1⇔-CLB2	[19]	+CLB6⇒-CLB2	[19]
			↑↓ CLB1⇔↑↓ CLB2	[21]
CLB5	+CLB6⇔+CLB5	[15]	-	-
CLB6	+CLB5⇔ +CLB6	[15]	-	-
MBP1	CDC34⇔±MBP1	[34]	↑↓ CDC34⇔↑↓ MBP1	[34]
CDC34	+MBP1⇔-CDC34	[34]	-	-
SKP1	+MBP1⇔-SKP1	[15]	↑↓ CDC34⇔↑↓ SKP1	[35]
SWI5	-	-	↑ CLN2⇔↓ SWI5	[18]
			± CLB1⇒ ± SWI5	[20]
			-CLB1-CLN3⇒+SWI5
CLN1	-	-	+SWI5⇒-CLN1	[20]
			-CLB2⇒+CLN1
CLB5	-	-	↑↓ CLN2⇔↑↓ CLB5	[18]

Classification rules with high accuracy in all three accuracy tests (CV-10 and cdc28, alpha-factor test sets) are shown in the upper part of the table. Questionable rules (see Classification rules for explanation) are shown in the lower part of the table.

ISSN: 1474-760X