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Figure 6 | Genome Biology

Figure 6

From: Microarray analysis of orthologous genes: conservation of the translational machinery across species at the sequence and expression level

Figure 6

Motifs found in upstream regions of genes involved in protein synthesis. (a-c) The motif logo and the distribution of scores from the matches of these motifs to the upstream regions of all yeast genes (dark blue) or just to those from which the motif was built (red). (a) The motif rap1 presents a periodicity that roughly corresponds to the pitch of a DNA helix and is similar to the sequence repeat found in telomeres, which is also targeted by the protein Rap1 [64]. (b) The motif rrpe contains an A-rich patch followed by a T-rich patch. The lengths of these two patches vary between genes. This motif may be palindromic. (c) The motif pac is made of highly conserved residues (around 100%) at several neighboring positions. (d) Ratio of genes in the cytoplasmic protein translation set and all S. cerevisiae genes matching at a given score to rap1 (purple), rrpe (red) and pac (orange) motifs.

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