Skip to main content
Figure 5 | Genome Biology

Figure 5

From: A gene-expression program reflecting the innate immune response of cultured intestinal epithelial cells to infection by Listeria monocytogenes

Figure 5

Comparison of gene expression in uninfected Caco-2 cells. Scatterplots were made of log-transformed ratios log2(Tn/T0) of (Caco-2 mRNA/reference pool mRNA). As the reference is relatively constant for each gene, scatter in the data represents biological variability in the Caco-2 cells. The scale for each plot is identical, with the axes ranging from log2(Tn/T0) -4 to 4. (a) Comparison of uninfected cells harvested several months apart. Correlation is poor (Pearson correlation coefficient 0.74). (b) Comparison of the same uninfected Caco-2 mRNA, hybridized on different days. Correlation is excellent (correlation coefficient 0.97), verifying reproducibility with respect to the reference pool. (c) Comparison of uninfected cells harvested from different plates on the same day. Correlation is good (correlation coefficient 0.94).

Back to article page