Figure 6
From: A new non-linear normalization method for reducing variability in DNA microarray experiments
Effects of normalization on R/G ratios of dye-swapped arrays. MA plots for replicate arrays A and B showing log(R A /G A ) (left column) log(R B /G B ) (centre column) and dye-swap normalized log((R A G B )/(G A R B )) (right column). The top row shows standard dye-swap normalization of otherwise unnormalized data. The middle and bottom rows show scaled print-tip lowess and scaled print-tip qspline normalization of the individual arrays and the subsequent dye-swap averaging normalization.