Figure 1

Conserved genome organization around the components of a putative Fe³⁺ siderophore transporter (from STRING [26,27] or from the literature when the genome is not present in STRING). Each gene is represented with an arrow-shaped box (as inSTRING) pointing in the direction of transcription. The genes in yellow contain the NEAT domain; the pink ovals indicate the number of occurrences of the domain within the gene. Genes in green are related to Escherichia coli fecB, fepB, or fhuD (Fe³⁺ siderophore transporter, periplasmic component). Genes in red are related to fecC, fepG, fhuB (Fe³⁺ siderophore transporter, transmembrane component). Genes in violet are related to fecE, fepC, fhuC (Fe³⁺ siderophore transporter, ATPase component). Remaining genes (in white) did not show significant sequence similarity to any of the other genes displayed in the figure. Codes for genes containing the NEAT domain are shown in Table 1. For the neighboring genes the names used correspond to those from the corresponding genomic project. Spy1797 should be shown between S_pyog (Spy1798) and Spy1796, but is not displayed here because there was no such corresponding entry in GenBank. Note that there was no neighboring ATPase (violet gene) in S. aureus; the most similar sequence in this species is SA0602 (not shown).