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Figure 7 | Genome Biology

Figure 7

From: Computational discovery of sense-antisense transcription in the human and mouse genomes

Figure 7

Splicing and mouse-human conservation patterns for sense and antisense ESTs from UniGene cluster Mm.10022. The graph depicts the exon-intron splicing structures of transcript sequences belonging to UniGene cluster Mm.10022. Organization of the figure as for Figure 2. The BOU mRNA (GenBank accession BC005773) is oriented from left to right with respect to genomic contig GA_x5J8B7W3T6H of the Celera mouse genome assembly. The mRNA is encoded by homer 3, a neuronal immediate early gene. The antisense species is homologous with a hypothetical human protein containing RNA helicase domains. This example is similar to Hs.47313 (Figure 2) in that the locations of strong mouse-human conservation in sub-regions within the 3' UTR of the sense transcript are coincident with the splicing structure of the antisense species.

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