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Table 4 Genes were ranked with the statistical methods in terms of degree of differential expression, and the number of true and false positives among the top 500 was counted. Above are the number of true and false positives in the top 500 when the proportion unchanged equals 5% and the number of genes equals 10000.

From: Ranking genes with respect to differential expression

Method

False positive

True positive

lognormal

samroc

262

238

t-test

296

204

Wilcoxon

303

197

Fold Change

454

46

MG

247

253

Bayes

284

216

SAM

286

214

normal

samroc

302

198

t-test

307

193

Wilcoxon

303

197

Fold Change

392

108

MG

454

46

Bayes

345

155

SAM

304

196