Table 1 Genes differentially expressed in ceramide-dependent apoptosis and involved in the ceramide and TNF-α pathways
From: Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays
Clone ID | GENX | GenBank accession number | Unigene | C. int. | C. SD | S. int. | S. SD | Ratio | Similarity | Gene symbol |
|---|---|---|---|---|---|---|---|---|---|---|
Genes involved in the C2-ceramide signaling pathway | ||||||||||
   yf59e08 | 5705 | R13531 | Hs.18858 | 3.56 | 0.54 | 12.01 | 0.86 | 3.37 | Phospholipase A2, group IVC (cytosolic, calcium-independent) | PLA2G4C |
   yf71a08 | 115123 | R12998; R40387 | Hs.194660 | 1.14 | 0.23 | 2.53 | 0.15 | 2.21 | Ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | CLN3 |
Genes transcriptionally stimulated by TNF-α | ||||||||||
   yg86b08 | 4272 | R53048; R53135 | Hs.43697 | 1.72 | 0.18 | 8.77 | 0.58 | 5.09 | Ets variant gene 5 (ets-related molecule) | ETV5 |
   yc86d06 | 5838 | F12910; T75064 | Hs.3281 | 3.61 | 0.48 | 11.54 | 0.61 | 3.19 | Neuronal pentraxin II | NPTX2 |
   yc88f11 | 197 | F10424; F12821 | Hs.78409 | 1.18 | 0.21 | 0.55 | 0.11 | 0.47 | Collagen, type XVIII, alpha 1 | COL18A1 |
   yf78g01 | 200888 | R14176; R40470 | Hs.76090 | 1.19 | 0.28 | 0.54 | 0.06 | 0.46 | TNF-α-induced protein 1 (endothelial) | TNFAIP1 |
Genes involved in the TNF-α signaling pathway | ||||||||||
   yf76d09 | 1017 | R13424; R40936 | Hs.83341 | 1.49 | 0.23 | 5.45 | 0.54 | 3.65 | AXL receptor tyrosine kinase | AXL |
   yg49f10 | 116415 | R20716 | Hs.79019 | 4.54 | 0.13 | 12.69 | 1.38 | 2.80 | Baculoviral IAP repeat-containing 1 | BIRC1 |
   c-26g10 | 1350 | F07467 | Hs.75551 | 1.37 | 0.27 | 2.81 | 0.56 | 2.05 | Ras suppressor protein 1 | RSU1 |
   c-08d10 | 4997 | F05370; Z38358 | Hs.151051 | 4.94 | 1.06 | 2.41 | 0.51 | 0.49 | Mitogen-activated protein kinase 10 | MAPK10 |