Genes concordantly expressed in vitro and in vivo following IL-2 exposure. The pattern of expression of genes identified as outliers (≥ 3-fold differential expression between test and reference samples) after IL-2 stimulation of cells in vitro (yellow bar), as in Figure 2, was compared to the expression pattern in lymphocyte/monocyte-enriched PBMC from gradient-separated blood of the same patient following intravenous IL-2 administration (720,000 IU/kg) (green bar). (a-e) Nodes from a cluster of 155 genes identified as differentially expressed in the in vitro time course. Only 51 of these are shown here. A smaller subset of 62 discordant genes is not shown.