Table 1 Allele frequency differentiation of drug metabolizing enzymes on the basis of "genetic clusters" versus "racial groups," from the data of Wilson et al. [2]

From: Categorization of humans in biomedical research: genes, race and disease

	Genetic clusters					Racial groups
	Allele frequencies				σ₂	Allele frequencies			σ₂
Locus	C	A	B	D		African	Caucasian	East Asian
CYP1A2	0.60	0.66	0.69	0.59	0.0023	0.58	0.68	0.67	0.0030
GSTM1	0.31	0.47	0.53	0.45	0.0087	0.33	0.49	0.52	0.0104
CYP2C19	0.27	0.09	0.37	0.25	0.0134	0.22	0.08	0.354	0.0182
DIA4	0.19	0.22	0.11	0.53	0.0340	0.21	0.21	0.32	0.0040
NAT2	0.46	0.74	0.17	0.33	0.0582	0.58	0.74	0.15	0.0931
CYP2D6	0.70	0.53	0.39	0.42	0.0197	0.70	0.49	0.37	0.0279

Genetic clusters: C, primarily African; A, primarily Caucasian; B, primarily Pacific Islander; D, primarily East Asian. Racial groups: East Asian denotes Chinese plus Papua New Guinean.

Back to article page