Skip to main content
Figure 2 | Genome Biology

Figure 2

From: Physical mapping of genes in somatic cell radiation hybrids by comparative genomic hybridization to cDNA microarrays

Figure 2

Mapping of retained human genomic sequences in a rodent cell. As a proof of principle, test genomic DNA from a monochromosomal CHO-human hybrid cell line containing the human X chromosome was co-hybridized with reference genomic CHO cell DNA on the microarray. Regions of increased fluorescence ratios in the test DNA, relative to reference DNA, are indicated in red. The magnitude of the increase in fluorescence ratios between the test and reference samples is indicated by the height of the line (log10 scale) compared with the baseline, which represents equal DNA copy numbers and has a fluorescence ratio of 1. Fluorescence ratios are drawn as a moving average of five adjacent genes/ESTs along the chromosome. Note the marked increased fluorescence ratios along the X chromosome (inset, with an expanded vertical scale).

Back to article page