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Figure 4 | Genome Biology

Figure 4

From: Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes

Figure 4

Phylogenetic tree constructed from the blocks identified by Block Maker using the parsimony method in PAUP 4.0b. Bootstrap values greater than 50% are indicated. Sequences from groups 1, 2 and 3 are colored red, green and blue, respectively. Accession numbers for putative GshA proteins from cyanobacteria are: Synechocystis sp., gi7469602; Nostoc punctiforme, gnl|DOE_63737|Contig399; Prochlorococcus marinus, DOE 59919 Contig26 gene 578; Synechococcus sp., nl|DOE_84588|Contig72. (Functions for these cyanobacterial proteins have not been experimentally verified. However, cyanobacteria are known to contain GSH [59] and the function of GshB in Synechococcus sp. PCC 7942 has been verified [60]. Thus, it is likely that these sequences indeed encode GshAs.) Other organism names and accession numbers are given in Table 2. Question marks indicate genera for which the ability to synthesize glutathione has not been demonstrated.

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