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Table 4 Pattern discovery at the level of binding sites

From: Evaluation of thresholds for the detection of binding sites for regulatory proteins in Escherichia coliK12 DNA

 

Consensus/Patser

Dyad-analysis/sweeping

Regulon

Sites/sites

250/sites

450/sites

Sites/sites

250/sites

450/sites

AraC

100.00

8.33

8.33

58.33

-

41.67

ArcA

76.47

76.47

47.06

76.47

-

76.47

ArgR

75.00

58.33

58.33

100.00

16.67

50.00

CRP

90.53

87.37

88.42

66.32

46.32

47.37

CysB

100.00

42.86

28.57

-

-

-

CytR

100.00

12.50

12.50

-

-

-

FIS

55.56

66.67

-

-

-

-

FNR

93.10

65.52

51.72

58.62

41.38

41.38

FadR

83.33

50.00

-

-

-

-

FruR

100.00

14.29

71.43

71.43

-

-

Fur

100.00

66.67

11.11

77.78

-

-

GlpR

60.00

40.00

40.00

80.00

33.33

46.67

IHF

72.22

66.67

22.22

50.00

-

-

LexA

100.00

88.89

88.89

100.00

100.00

100.00

Lrp

78.95

47.37

26.32

36.84

-

-

MalT

66.67

22.22

22.22

55.56

44.44

77.78

NR_I

77.78

55.56

55.56

77.78

77.78

77.78

NagC

57.14

14.29

14.29

-

-

28.57

NarL

75.00

35.00

15.00

55.00

-

-

OmpR

71.43

-

7.14

42.86

-

-

OxyR

75.00

25.00

-

-

-

-

PhoB

71.43

57.14

57.14

71.43

71.43

42.86

PurR

92.86

85.71

78.57

92.86

78.57

85.71

TrpR

100.00

100.00

100.00

100.00

100.00

100.00

TyrR

86.67

73.33

66.67

53.33

46.67

60.00

Average

88.59

60.36

53.07

75.19

70.76

65.64

  1. For each family, we show the results of applying Dyad-analysis/sweeping and Consensus/Patser to the problem of discovering binding sites. The results contain pattern discovery data similar to those in Table 3, but this time counting the number of binding sites found per total number of sites. Again, only dyads extracted from max ROMs are used. The names of columns are as described in Table 3.