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Table 1 Lists of specificity-determining residues as predicted by different methods

From: Using orthologous and paralogous proteins to identify specificity determining residues

Method

DNA-binding Domain

Ligand-binding Domain

Model 1, eq (3)

P < 10-5I > 1.0 : 15,16,50,55

P < 10-5I > 1.5 : 98,114,122,146,147,160,221,249

Model 1, eq (4)

P < 10-4I > 1.0 : 15,16,50,55

P < 10-4I > 1.5 : 98,114,146,160,221

Model 2

P < 10-2 : 15,16,55

P < 10-2 : 85,98,122,146,160,221,246,249

  1. Numbering is according to 1wet PDB file. See Supplementary Information for equations and details.
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Genome Biology

ISSN: 1474-760X

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