Figure 1

Cdc42- and Rac-interacting proteins in the species discussed in the text. Rac and Cdc42 effectors are grouped into three categories: non-kinases, kinases, and lipid-modifying enzymes. These effectors are represented in the different species by colored lines according to their binding abilities: yellow for Rac, blue for Cdc42, and green for both. The absence of a line means that no homolog is known from current databases, and gray lines indicate that the homologous protein is present in the organism but has not yet been shown to interact with Cdc42 or Rac. The names of CRIB-domain-containing effectors are written in red.