Table 1 Identity of genes differentially expressed between naive and experienced honeybees and in caffeine-treated honeybees
Array data | ||||||
|---|---|---|---|---|---|---|
bEST number | Gene | Head (foragers vs naive) | Abdomen (foragers vs naive) | Head (caffeine treated vs control) | Predicted function | Similarity to closest relative (%) |
5 | Hsc70 | -1.6 | +1.3 | +12.6 | Chaperone, heat shock response, neurotransmitter release | 95% |
22 | α-Gluc-1 | +2.5 | -1.1 | +2.2 | α-Glucosidase | 100% |
28 | Unknown | -3.2 | +2.3 | -1.5 | Unknown | N/A |
30 | Hsp20 | +1.3 | +2.1 | -1.1 | Chaperone | 65% |
31 | Hsp83 | -1.6 | +2.4 | +1.2 | Chaperone, heat shock response, protein folding | 92% |
36 | SPARC | -8.2 | -3.5 | +1.8 | Cell adhesion, calcium binding | 61% |
54 | GPDH 2 | -3.1 | +1.3 | -1.1 | Mitochondrial glycerol-3-phosphate dehydrogenase | 69% |
56 | Cox10 | -4.0 | -1.1 | -1.2 | Protoheme IX farnesyltransferase, cox assembly | 76% |
57 | Stck | -2.6 | -1.5 | +3.9 | LIM-domain protein, transcriptional regulation | 88% |
61 | Unknown | -5.2 | -1.3 | +1.4 | PDZ-domain protein, signal transduction | 50% |
82 | Aminopeptidase-1 | +1.6 | +1.0 | -1.2 | Membrane alanyl aminopeptidase | 51% |
92 | Trf | +1.2 | +3.0 | +2.8 | Iron transport, iron homeostasis, defense response | 63% |
97 | CG16857 | -3.3 | +2.1 | +1.5 | Ig-domain protein, cell adhesion | 63% |
99 | RpS19 | -4.7 | -1.7 | -1.6 | Structural protein of ribosome, protein biosynthesis | 83% |
102 | MRJP2 | +12.1 | +1.7 | -1.3 | Royal-jelly protein | 100% |
105 | Gld | +3.0 | -1.0 | +2.0 | Glucose dehydrogenase | 100% |
108 | PPIase | -4.0 | -1.1 | -1.5 | Peptidylprolyl isomerase | 92% |
109 | ATP synthase β | -5.9 | -1.4 | +1.6 | Hydrogen-transporting two-sector ATPase | 95% |
112 | Unknown | +5.5 | -1.1 | -1.3 | Unknown | N/A |
121 | IDGF | -1.4 | +1.9 | +2.4 | Imaginal disc growth factor, not chitinase | 54% |
122 | α-Glucosidase-2 | -2.3 | +9.8 | +1.2 | α-Glucosidase | 60% |
123 | Unknown | -3.3 | -1.1 | -1.7 | Unknown | N/A |
124 | Peritrophin | -5.6 | -4.3 | +1.4 | Structural protein of peritrophic membrane, chitin binding | 78% |
125 | Hymenoptaecin | +1.5 | +8.0 | +1.7 | Antibacterial protein, defense response | 100% |
127 | CG6112 | -7.1 | -3.8 | -1.3 | Ligand-gated ion channel subunit | 98% |
128 | Aminopeptidase-2 | -1.4 | -1.2 | +1.5 | Membrane alanyl aminopeptidase | 49% |
129 | Unknown | -1.9 | +1.2 | +5.6 | Unknown | N/A |
130 | Unknown | -7.2 | -1.7 | -1.1 | Unknown | N/A |
131 | Lectin | -16.0 | -5.9 | -1.3 | Ligand binding or carrier | 82% |
132 | CoxI | -4.9 | +1.0 | +1.1 | Respiratory-chain enzyme | 100% |
133 | Scp1 | -2.4 | -1.2 | -1.7 | Small chemosensory protein | 74% |
134 | ATPsynthase F0-6 | -14.1 | -1.4 | -1.0 | Proton pump, ATP synthesis | 100% |
136 | Unknown | N/A | +1.2 | +4.3 | Unknown | N/A |
138 | Gs2 | N/A | +1.8 | +3.5 | Glutamine synthase | 77% |
143 | Unknown | N/A | -1.0 | +3.4 | Unknown | N/A |
147 | CG5586 | N/A | -1.3 | -3.2 | WD40 and SOCS domain-containing protein | 38% |
148 | Aminotransferase | -2.6 | -1.4 | -3.5 | Ornithine-oxo-acid aminotransferase | 73% |