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Figure 2 | Genome Biology

Figure 2

From: Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophilagenome

Figure 2

VISTA plot of genome organization and sequence conservation in the Drosophila eve region. Sequences were aligned using AVID, and conserved sequences were visualized using default parameters of VISTA. From top to bottom are pairwise comparisons between D. melanogaster and D. erecta (mel-ere), D. pseudoobscura (mel-pse), D. willistoni (mel-wil) and D. littoralis (mel-lit), respectively. In each panel, conserved segments from 50-100% are plotted, with the midline indicating 75% identity; regions with no midline represent sequences not sampled in a pairwise comparison. Double bars crossing a midline represent rearrangement breakpoints. The location and orientation of coding sequences are indicated by arrows; purple boxes represent coding exons and light-blue boxes represent functionally characterized cis-regulatory sequences [50,88,89,90]; pink regions represent uncharacterized CNCSs. Suffixes on gene names (for example, TER94-RA) indicate the particular transcript displayed for genes with multiple transcripts. Note that the predicted gene CG12133 is restricted to the D. melanogaster/D. erecta lineage but is absent in D. pseudoobscura, although both flanking genes are present.

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