In silicodiscovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases

Table 1 Summary of genes surveyed within chronic alcohol withdrawal QTLs on proximal chromosome 1 and chromosome 13

	Number of genes	Base-pairs	% Coverage*			Number of amino-acid changes^†	Number of genes with at least one amino-acid change^†
			B6	D2	Both
Chromosome 1	121	125,385	84 (85)	77 (80)	67 (70)	8 (8)	6 (6)
Chromosome 13	78	84,635	89 (90)	57 (59)	52 (55)	36 (45)	15 (19)
Total	199	210,020	86 (87)	69 (71)	61 (64)	44 (53)	21 (25)

*The first number listed indicates in silico percent coverage; numbers in parentheses indicate percent coverage after in-house sequencing was done to fill in gaps in the in silico alignment. ^†The first number indicates changes where multiple reads were available in each strain or the change has been verified by in-house sequencing; the number in parentheses includes changes where only one read was available for either B6 or D2.

ISSN: 1474-760X