Identification and utilization of arbitrary correlations in models of recombination signal sequences

Table 5 Frequency of above-threshold scores for non-RSS

			Number of physiologic RSS scoring below the indicated score
			0	1	2	3	4	5	6	7	8	9	10
12-RSS	RIC	Score	-48.16	-45.81	-38.81	-38.81	-38.21	-37.77	-37.48	-36.03	-36	-35.01	-34.44
		Count	859	449	54	54	48	40	34	16	16	10	10
		Frequency	0.00414	0.00212	0.00025	0.00025	0.00023	0.00019	0.00016	0.00008	0.00008	0.00005	0.00005
	WM1	Score	-46.32	-40.87	-37.75	-37.6	-36.33	-35.29	-34.63	-33.73	-32.73	-32.73	-32.69
		Count	2372	458	169	161	76	43	35	22	12	12	12
		Frequency	0.01118	0.00216	0.00080	0.00076	0.00036	0.00020	0.00017	0.00010	0.00006	0.00006	0.00006
	WM0	Score	-46.86	-44.61	-42.83	-39.33	-39.06	-38.58	-38.58	-35.23	-34.59	-34.45	-34.21
		Count	1067	632	405	115	99	83	83	30	19	17	15
		Frequency	0.00503	0.00298	0.00191	0.00054	0.00047	0.00039	0.00039	0.00014	0.00009	0.00008	0.00007
23-RSS	RIC	Score	-69.69	-66.37	-64.84	-58.45	-57.45	-57.41	-55.61	-54.35	-54.3
		Count	2460	1147	791	100	71	69	37	26	26
		Frequency	0.01160	0.00541	0.00373	0.00047	0.00033	0.00033	0.00017	0.00012	0.00012
	WM1	Score	-65.24	-63.84	-57.58	-54.55	-54.52	-54.16	-52.96	-52.55	-48.5
		Count	3126	2309	471	190	189	167	109	97	14
		Frequency	0.01474	0.01089	0.00222	0.00090	0.00089	0.00079	0.00051	0.00046	0.00007
	WM0	Score	-63.22	-61.52	-58.9	-58.74	-56.46	-56.46	-55.91	-52.41	-52.17
		Count	2481	1691	816	777	365	365	317	82	72
		Frequency	0.01170	0.00797	0.00385	0.00366	0.00172	0.00172	0.00149	0.00039	0.00034

Scores for physiologic RSS were ranked in ascending order so that the lowest score was ranked 0, the second lowest score was ranked 1, and so on. For each score, the number of physiologic RSS with a lower score is equal to this rank. We took the lowest 5% of scores under each model as the test thresholds for that model: ranks 0 through 10 were used for the three 12-RSS models and ranks 0 through 8 were used for the three 23-RSS models. For each of these threshold scores, we counted the number of non-RSS in the chromosome 8 sequence AC084823 that scored above the threshold. The threshold score, the count, and its relative frequency are shown.