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Figure 7 | Genome Biology

Figure 7

From: Identification and utilization of arbitrary correlations in models of recombination signal sequences

Figure 7

RIC models are better at recognizing pseudogene-associated RSS. The scores for sequence AE000663 under the RIC23 model are plotted against the scores under the WM023 model (left panel) or the WM123 model (right panel). RIC23 scores are shown on the y-axis, and WM123 or WM023 scores are shown on the x-axis. The y = x line is shown in red. AE000663 contains seven Vβ pseudogenes and nine functional Vβ gene segments. Blue points indicate scores for non-RSS, red points indicate scores for pseudogene-associated RSS, and the red triangles indicate scores for RSS associated with functional gene segments. The horizontal gray line is halfway between the lowest RIC23 score for a physiologic RSS distinguishable from non-RSS scores (-46.08.) and the highest RIC23 score for a non-RSS (-49.09): -46.08 - 1.505 = -47.585 = -49.09 + 1.505. The vertical gray line is the same distance below the corresponding WM123 or WM023 score: -46.02 - 1.505 or -47.52 - 1.505, respectively.

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