Figure 1

Three comparative genomics methods for identifying functional links between genes and the networks they produce. The schematics on the left show links between gene A (pink) and gene B (blue) based on (a) the same phyletic distribution across the known genomes, here arbitrarily labeled W, X, Y, Z, etc.; (b) their proximity on chromosomes from different genomes; and (c) fusion of A and B into one multidomain gene in another organism. On the right are networks found in H. pylori using each of the three methods. All network figures were made using the Pajek program [42].