Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes

Table 1 Genes predicted on the BMBAC01L03/BMBAC01P19 contig

B. malayi open reading frame	Predicted cDNA length (bp)	Predicted peptide length	Number of introns	C. elegans ortholog	Percent identity with C. elegans ortholog	Number of introns in C. elegans ortholog	Number of shared intron positions with C. elegans ortholog	Putative identity
BMBAC01L03.1	1340*	446*	7*	CeF14B4.3	58^†	3^‡	3	Amino-terminal fragment of the β subunit of RNA polymerase I
BMBAC01L03.2	693	230	6	CeF43G9.5	68	3	1	Pre-mRNA cleavage factor
BMBAC01L03.3	1239	412	8	-	-	-	-	Contains LON-ATP-dependent serine protease domain
BMBAC01L03.4	630	209	2	CeF39B2.10	57^§	3	1	Contains dnaJ domain
BMBAC01L03.5	918	305	6	CeF43G9.3	58	6	2	Mitochondrial carrier protein
BMBAC01P19.1 (Bm-mif-1)	535	115	2	CeY56A3A.3	41	2	2	Macrophage-migration- inhibitory factor homolog
BMBAC01P19.2a/b (Bm-pbr-1)	5955/5748	1934/1865	37/35	CeC26C6.1	34	14	9	Polybromo domain protein, BAF180 homolog
BMBAC01P19.3 a/b	1182/919	367/283	9/7	CeF43G9.4	44^¶	8	2	Contains PWWP domain
BMBAC01P19.4 (Bm-dap-1)	446	111	1	CeT28F4.5	30	1	1	Homolog of mammalian death- associated protein DAP-1
BMBAC01P19.5a/b (Bm-ubr-1)	2679/2602	847/821	18/17	CeT28F4.4	27	12	5	Unknown
BMBAC01P19.6	804	190	4	CeF31C3.5	41	1	1	Conserved protein of unknown function
BMBAC01P19.7a/b	1039/932*	274/298*	6/7*	CeC36B1.12	60^#	3^‡	2	Carboxy-terminal fragment of a novel transmembrane protein

*Gene fragments (see text). ^†BMBAC01L03.1 gene fragment aligned with the amino-terminal 450 amino acids of CeF14B4.3. ^‡Number of introns in the aligned portion of the C. elegans ortholog. ^§Percent identity over the dnaJ domains of BMBAC01L03.4 and CeF39B2.10. ^¶ Percent identity over the PWWP domains of BMBAC01P19.3 and CeF43G9.4. ^#The gene fragment of BMBAC01P19.7 aligned with the carboxy-terminal 380 amino acids of CeC36B1.12.

ISSN: 1474-760X