Table 3 A comparison between amino-acid composition of the conserved residues in the TM-helices of 45 transporter Pfam-A families and that of the other 123 Pfam-A families
From: Genomic analysis of membrane protein families: abundance and conserved motifs
Amino acid | Conserved residues in TMs of transporter families (%) | Conserved residues in TMs of the other families (%) | Ratio |
G | 31.4 | 15.6 | 2.0 |
N | 3.2 | 2.5 | 1.3 |
P | 10.3 | 8.0 | 1.3 |
D | 2.3 | 1.9 | 1.2 |
R | 1.8 | 1.5 | 1.2 |
A | 8.6 | 7.7 | 1.1 |
Q | 2.3 | 2.1 | 1.1 |
T | 3.9 | 4.0 | 1.0 |
W | 3.6 | 3.8 | 0.9 |
E | 1.9 | 2.1 | 0.9 |
S | 4.4 | 5.4 | 0.8 |
F | 7.5 | 9.6 | 0.8 |
K | 0.9 | 1.2 | 0.8 |
Y | 3.5 | 5.1 | 0.7 |
L | 8.4 | 13.1 | 0.6 |
V | 2.3 | 4.6 | 0.5 |
M | 0.6 | 1.6 | 0.4 |
I | 1.9 | 5.2 | 0.4 |
H | 0.9 | 3.6 | 0.2 |
C | 0.1 | 1.6 | 0.1 |