Figure 3
From: Molecular archeology of L1 insertions in the human genome
Nucleotide profile of L1 target loci. (a) Logo graphics were generated for the TSDs of length shown and 10 nucleotides of upstream and downstream flanking sequence. At each position, the highest-frequency base is at the top of the stack, and so the general consensus can be found by reading the top base at every position. The relative height of individual bases at each position is proportional to the frequency of the base at that position. The vertical axis represents the amount of information in the input data. The TSDs included in this analysis did not have any mismatches. Stars indicate the first position of the TSD. The nucleotides are colored as follows: A, green; T, red; C, blue; G, yellow. (b) The percentage of A, T, G, and C nucleotides is shown, calculated for 1,794 15-nucleotide TSDs (without mismatches) and their flanking regions (50 nucleotides on each side). The shaded region represents the TSD sequence.