Figure 2
From: Reassignment of specificities of two cap methyltransferase domains in the reovirus lambda2 protein
Sequence alignment of the predicted human reovirus cap 1 MTase with its counterpart from grass carp reovirus (GCRV) and vaccinia virus (VP39). Residues that are invariant between the reoviruses and those predicted to participate in binding of the AdoMet, the cap moiety, and in catalysis in all cap 1 MTases, are highlighted in black; other conserved residues are highlighted in gray. Motif nomenclature follows [12].