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Table 1 Chromosomal localization of human Smads

From: The Smads

Name

Previous names

Chromosomal

Gene name

OMIM ID

Unigene

  

localization

  

accession number

TGFβ/activin-regulated R-Smads

     

   Smad2

MADR2, JV18-1

18q21.1

MADH2

601366

NM005901

   Smad3

JV15-2

15q21-q22

MADH3

603109

NM005902

BMP-regulated R-Smads

     

   Smad 1

MADR1, JV4-1, Dwarfin A, bsp-1

4q28

MADH1

601595

NM005900

   Smad 5

DwarfinC, JV5-1

15q31

MADH5

603110

NM005903

   Smad 8

Smad9, MADH6

13q12-q14

MADH9

603295

NM005905

Common Smad

     

   Smad 4

DPC4

18q21.1

MADH4

600993

NM005359

Inhibitory Smads

     

   Smad 6

JV15-1

15q21-q22

MADH6

602931

AF035528

   Smad 7

 

18q21.1

MADH7

602932

NM005904

  1. Further information for each Smad is available by searching under the Gene Name in the Gene Card database [11] and using the OMIM ID number at the Online Mendelian Inheritance in Man database [32].