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Table 3 Comparison of recombination characteristics of RI sets

From: The genetic structure of recombinant inbred mice: High-resolution consensus maps for complex trait analysis

  N N Total New Total Total %   % R
RI set strains* typed** markers markers† SDPs R SDP DR DR Per strain
AXB-BXA 37 (28) 37 (41) 965 577 669 1775 37.3% 114 12.8% 43.3
BXD 35 (34) 36 936 551 623 1492 41.2% 95 12.7% 41.4
BXH 16 (16) 19 768 739 436 848 50.2% 82 19.3% 44.6
CXB 13 (13) 13 867 687 406 671 58.8% 63 18.8% 51.6
BXN 104 (91) 109 1575 1575 1220# 4786 25.4% 354 14.8% 43.9
  1. Column definitions: Total SDPs is the total number of unique strain distribution patterns identified in each set. Total R is our estimate of the total number of independent recombinations represented in each complete set of RI strains including members of RI sets that are now extinct. This number will underestimate true numbers of recombination breakpoints by about 7.5% due to the limited number of available markers on some chromosome regions. % SDP is our estimate of the percentage of the total number of SDPs that have actually been identified in association with particular markers. DR is the sum of recombinations associated with double recombinant haplotypes (see text) in each RI set. % DR is the percentage of recombinations associated with these double recombinant haplotypes. R per strain is the estimate of the average number of recombination events accumulated by individual RI strains. *Total number of genetically independent strains per RI set genotyped in this study. The numbers in parentheses are numbers of strains available as live stock from the Jackson Laboratory. **Total number of strains per RI set genotyped in all studies. We genotyped 107 of these 109 strains (BXA9 and BXD41 were not genotyped). Four of the AXB-BXA strains are not genetically independent and the effective number of genotyped strains is actually 37 rather than 41. † This number includes both newly genotyped markers and makers for which genotypes were changed as a result of retyping. # Due to overlap of SDPs this number is not a sum of the overlying four values. The total number of unique SDPs was computed from the composite BXN set directly.