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Table 1 Genes differentially expressed in response to lab overexpression

From: Identification of candidate downstream genes for the homeodomain transcription factor Labial in Drosophila through oligonucleotide-array transcript imaging

Functional class Genes on the array (N) Differentially expressed transcripts (n) n/N × 100 (%) Down-regulated Up-regulated
Signal transduction 107 5 4.7 2 3
Transcriptional regulation 263 20 7.6 14 6
Cell cycle 37 5 13.5 0 5
Cytoskeleton/structural proteins 149 5 3.4 4 1
Metabolism 315 13 4.1 6 7
Translation 59 1 1.7 1 0
Heat-shock proteins 18 * * * *
Transcription/replication/repair 73 4 5.5 0 4
Proteolytic systems/apoptosis 62 12 19.4 1 11
Cell surface receptors/CAMs/ion channels 181 12 6.6 10 2
Transposable elements 35 4 11.4 3 1
Chromatin structure 36 4 11.1 2 2
RNA binding 59 7 11.9 2 5
Secreted proteins 34 2 5.9 2 0
Unknown function 85 2 2.4 1 1
  ΣN = 1513 Σn = 96   48 48
  1. Genes that are differentially expressed following heat-induced ubiquitous overexpression of lab in stage 10-17 hs-lab embryos, grouped according to functional classses. *The functional class 'heat-shock proteins' was excluded from the analysis (see Materials and methods). N, number of genes within a functional group present on the chip; n, number of genes differentially expressed within a functional group following lab overexpression; n/N × 100, number of differentially expressed genes within a functional class following lab overexpression, given as a percentage of the total number of genes in this class present on the array; downregulated, total number of genes within each functional class differentially downregulated following lab overexpression; upregulated, total number of genes within each functional class differentially upregulated following lab overexpression.