Figure 2
From: Nuclear dynamics: where genes are and how they got there
Chromatin and nuclear bodies. The micrograph shows the separate detection in the same HeLa cell nucleus of bulk chromatin (blue), the nucleolar protein fibrillarin (red), the RNA-splicing factor ASF/SF2 (green), and the Cajal body (formerly coiled body) autoantigen p80coilin (magenta). The right-hand panel shows an overlay of the four separate signals. Nuclear Cajal bodies contain both p80coilin and fibrillarin (arrows). ASF/SF2 localizes in nuclear speckles. Scale bar = 5 μm.