Table 3 PROSITE sequence motifs located using ProfileScan in proteins involved in the sister chromatid cohesion mechanism
From: The cohesin complex: sequence homologies, interaction networks and shared motifs
Protein class | S. cerevisiae proteins | PROSITE motifs |
|---|---|---|
Cohesin subunits | Smc1 | NLS_BP: Bipartite nuclear localization signal |
| Â | Â | ATP_GTP: (P loop) (Walker A motif) |
| Â | Â | DA_BOX: Walker B motif |
| Â | Â | Leucine zipper |
| Â | Smc3 | NLS_BP: Bipartite nuclear localization signal |
| Â | Â | ATP_GTP: (P loop) (Walker A motif) |
| Â | Â | DA_BOX: Walker B motif |
| Â | Â | Leucine zipper |
| Â | Scc1 | None |
| Â | Scc3 | NLS_BP: Bipartite nuclear localization signal |
Loading factors | Scc2 | Leucine zipper |
| Â | Scc4 | AMP binding domain |
SMC1-interacting protein | Trf4 | NLS_BP: Bipartite nuclear localization signal |
| Â | Â | PAP: poly(A) polymerase |
| Â | Â | PAP_associated: poly(A) polymerase associated |
| Â | Â | PAP_core: poly(A) polymerase core |
SMC1-interacting | Tid3/NCD80 | None |
Scc1-interacting | Esp1 | PROKAR_LIPOPROTEIN prokaryotic membrane lipoprotein attachment site |
| Â | Â | NLS_BP: Bipartite nuclear localization signal |
SCC2-interacting | Prp11 | ZF_MATRIN domain: RNA-binding zinc finger |