| All†| Selected‡ |
P
§
|
---|
Human versus rodent* |
Ks | 0.496 ± 0.14 | 0.692 ± 0.19 | 4.5 × 10-3 |
Ka | 0.079 ± 0.08 | 0.349 ± 0.08 | 2.4 × 10-7 |
Ka/Ks | 0.147 ± 0.13 | 0.537 ± 0.18 | 1.3 × 10-5 |
Mouse versus rat¶ |
Ks | 0.172 ± 0.06 | 0.193 ± 0.07 | 0.57 |
Ka | 0.029 ± 0.03 | 0.148 ± 0.04 | 5.7 × 10-3 |
Ka/Ks | 0.161 ± 0.16 | 0.787 ± 0.12 | 2.0 × 10-3 |
- *Average Ks and Ka for the human-mouse and human-rat pairwise comparisons. †Average and standard deviation values for all protein sets. ‡Average and standard deviation values for the protein sets identified as having accelerated rates of amino-acid substitution. §P value associated with a t-test comparing the means of the all versus selected protein sets. ¶ Average Ks and Ka for the mouse-rat pairwise comparisons.