Figure 3
Multiple alignment of the archaea-specific family of predicted metallo-β-lactamase superfamily hydrolases that includes the alleged archaeal dihydropteroate synthase, MJ0301. The scheme for displaying multiple alignments is as described in the legend to Figure 1. A consensus secondary structure was derived from the crystal structure metallo-β-lactamases from Stenotrophomonas maltophilia (1SML) and Bacteroides fragilis (1A7T). Residues are colored at 90% consensus. Bfr, Bacteroides fragilis; Bsp, Bacillus species 170; Mj, M. jannaschii; Mth, M. thermoautotrophicum; Pab, P. abyssi; Ph, P. horikoshii; Stma, S. maltophilia; Tm, Thermotoga maritima.