Table 8 Examples of differential genome display of Pyrococcus abyssi and Pyrococcus horikoshii using the COG approach

Present in P.abyssi but not P. horikoshii

   PAB2044/0547

amt-szyqvdcebrhuj- - - - - -n-

Anthranilate phosphoribosyltransferase

The entire branched pathway for aromatic amino acid biosynthesis appears to be present in P. abyssi but not in P. horikoshii

   PAB2045/0147

amt-szyqvdcebrhuj- - - - - -n-

Anthranilate synthase component I

   PAB2046/0512

amt-szyqvdcebrhuj- - - - - -n-

Anthranilate synthase component II

   PAB0307/0082

- - - -szyqvdceb-huj- - - - -inx

DAHP synthase

   PAB2049/0159

amt-szyqvdcebrhuj- - - - -in-

Tryptophan synthase a subunit

   PAB2048/0133

amt-szyqvdcebrhuj- - - - -in-

Tryptophan synthase ß subunit

   PAB0250/0031

- - - -szyqvdcebrhuj- - - - - -n-

Cysteine synthase

P. abyssi appears to be the only euryarchaeon that encodes the typical cysteine biosynthesis pathway which it shares with A. pernix

   PAB1595/2046

a- - -szyq-dc-b- - -j- - - - - - - -

ATP sulfurylase

   PAB0781/0529

a- - -szyq-dcebr- -j- - - - - -n-

Adenylylsulfate kinase

   PAB1839/0035

- -t-szyqvdcebrh-jwgp-l-n-

Uracil phosphoribosyltransferase

   PAB2246/0827

-m- -s- - - - - - -brhu-w-p- - - - -

Adenine-specific DNA methyltransferases

   PAB2154/0610

amt-s- - - - - -e- -hujw-p- - -n-

Restriction enzymes type I helicase subunit

Present in P. horikoshii but not P. abyssi

   PH0369/0153

- - -k- -y-v- -ebrh- - - - - -I---

Galactokinase

   PH1048, PH1046/2309

- - -k-z-q-d- -b- - - - - - -o- - - -

Leucyl aminopeptidase (aminopeptidase T)

   PH0365/1085

a- -k- -y-v- -e-rh- - - - - - - - - -

Galactose-1-phosphate uridylyltransferase

   PH0896/1230

- - -k- -yqvd-eb- - -j- - - - - -n-

Co/Zn/Cd efflux system component

   PH0162/1353

amtk- - -qv- - - -r- - - - - - - - - - -

Predicted hydrolase of the HD superfamily

   PH1032/0338

-m-k- - - - - -ce- -hu- - - - -I- - -

Site-specific DNA methylase dam

   PH0873/1401

- -tk- - -q-dceb-uj- - - - - - - -

GTPase subunit (McrB) of a restriction endonuclease