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Table 7 A. pernix proteins conserved in a wide range of organisms but missing in euryarchaea (examples)

From: Towards understanding the first genome sequence of a crenarchaeon by genome annotation using clusters of orthologous groups of proteins (COGs)

A. pernix gene/COG number Phylogenetic pattern* Function Comments
APE1618/1048 - - - - -zyq-d-ebr- - - - - - - - - -x Aconitase A Unlike other archaea with sequenced genomes, A. pernix is an aerobe and possesses the complete TCA cycle. APE1618 belongs to a distinct family of (otherwise) bacterial aconitases (e.g E. coli AcnA and B. subtilis CitB). APE1816 also belongs to a specific family of bacterial fumarases.
APE1816/0114 - - - - -zy- -dcebrhu- - - - - -i-x Fumarase  
APE1677/1071 - - - - -zy- -dc-br- - - -gp- -i-x pyruvate dehydrogenase E1 component, a-subunit  
APE1674/0022 - - - - -zy- -dc-br- - - -gp- -i-x pyruvate dehydrogenase E1 component, ß-subunit  
APE1671/0508 - - - - -zy- -dcebrh- - -gp- -i-x Dihydrolipoamide acyltransferase  
APE1725/1290 - - - - -z-q-dc-br-uj- - - - - -nx Cytochrome b As an aerobe, A. pernix encodes specific electron-transport chain components. APE1623 is closely related to the ortholog from Aquifex aeolicus.
APE1623, APE0793_1/0843 - - - - -z-q-dcebr-uj- - - - - -nx Cytochrome c oxidase, heme b and copper-binding subunit  
APE0793_2/ - - - - -z-q-dcebr- - - - - - - - - -x Cytochrome oxidase, subunit 3  
1845    
APE1498/1171 - - - - -zy-vdcebrh- - - - - - - - -x Threonine dehydratase Specifically related to a subfamily of bacterial catabolic threonine dehydratases (e.g. E. coli TdcB)
APE1038/0295 - - - - -zy-vd-ebrh- -wgpo- - - - Cytidine deaminase  
APE1353/0514 - - - - -zy-dceb-h- - - - - -l- - - DNA helicase (RecQ family) APE1353 differs from other members of the RecQ family by the presence of long amino-terminal extension that probably form a non-globular domain. APE1353 shows no specific affinity to any of the bacterial orthologs.
APE2450/0260 - - - - -z-q-dcebrhu-wgp- -i-x Leucyl aminopeptidase  
APE0137/0405 - - - - -zy- -dcebr-u- - - - - - - - - Gamma-glutamyltranspeptidase  
APE2464/ - - - - -z-qvdcebr- - - - - - - - - - - Phosphate starvation-inducible protein  
COG1702   PhoH, Predicted ATPase  
APE0993/>0813 - - - - -z- - -d-eb-hu-wgp-l- - - Purine-nucleoside phosphorylase Correlates with the absence of de novo purine biosynthesis and the probable importance of salvage pathways
APE2105/0813a - - - - -z- - - - - -e- -h- - - - -l- - - Uridine phosphorylase  
APE0033/1866 - - - - -zy- -d-eb-h- - - - - - - - - - Phosphoenolpyruvate carboxykinase  
  1. *The designations are as in Table 6.