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Table 2 Functional classification of cell-cycle-regulated transcripts found in Nb2 cells

From: Analysis of prolactin-modulated gene expression profiles during the Nb2 cell cycle using differential screening techniques

Category Transcript
Cell cycle: cyclins and cell-cycle regulators  
   Transcripts that have a cell-cycle-modulated homolog in yeast Cyclin E1 [78], peaks in G1
  EGR-1, immediate-early gene (constitutive expression in Nb2 cells)
  Cdc5-like protein [79], peaks in M
  Cdk2, Cdk5 [78], peak in G1
   Cell-cycle-modulated transcripts with a yeast homolog (not modulated) Cyclin B1, peaks in G2/M
   Cell-cycle-modulated transcripts with no yeast homolog Cyclin B2, peaks in G2
  Cyclin D2 [8], peaks in G1
  Cyclin D3 [8], peaks in G1
Nucleotide metabolism, DNA replication and repair Cdc21 homolog
  Spermidine/spermine N-acetyl transferase (SSAT)
  Ornithine decarboxylase (ODC) [80]
  S-adenosylmethionine decarboxylase [80]
  Prothymosin a
  PARP-2 (Unknown 6-45)
Chromatin structure Histones H2A, H2B, peak in S in mammals and in yeast
Cytoskeleton Myosin heavy chain
  Tubulin a, ß
  ß-actin [6]
  Clone 15 = rNUDC [81]
  FAK p125
Cell-surface antigens, adhesion molecules and signaling molecules  
(involved in apoptosis, survival and/or proliferation)  
   Growth factor FGF-2 [82]
   Surface molecules Prolactin receptor Nb2 form [16]
  T-cell receptor ? chain [17]
  T-cell receptor a chain [17]
  GnRH receptor [83]
  Glucocorticoid receptor
  Galectin-8
  Leukocyte membrane glycoprotein, CD45
  Vitamin D3 receptor
  Thromboxane A2 receptor
  ß2-microglobulin
Cytoplasmic and/or nuclear signaling molecules p38 Map kinase [21]
  Pim-1 [9]
  Gfi-1 [10]
  Stathmin [84]
  P13 kinase p110 a
  Phospholipase C?1
  14-3-3 ? and e
  Bax
  p53
  RexB/NSP
  Phosphatidylinositol transfer protein
  a 4 phosphoprotein [79]
Transcription factors IRF-1 [7]
  c-Myc [18]
  c-Fos (not in Nb2 cells [18])
  MRG1-related protein
  E2F-1 [78]
  Zfx
Heat shock, stress response and chaperones Cyclophilin (B)
  TCP-1 e and ?
  Hsp70 (not expressed in Nb2 cells)
  Hsp70-like = Nb29 [41]
  Hsp27
  Hsp86
  ß-actin
  a2-tubulin
  Rdnuc (Golgi-associated protein) [11]
  Myosin heavy chain
  Focal adhesion kinase (FAK)
Metabolism (energy) Phosphoglycerate kinase
  Enolase a
  Aldehyde dehydrogenase
  ATP synthase ß subunit
Protein and RNA synthesis, modifications and degradation  
   Ribosomal proteins L3, L12, L13A, new ribosomal protein L15 type (unknown 4-27)
  S8, S13
   Glycosylation factor Itm1
   Elongation factor EF-2 [77]
Inter-compartment transport and trafficking CRM-1 = exportin 1
  Sec-22
  Glycine transporter
  Unknown 4-58 (SH3, Rab GAP, TBC domain: putative nuclear pore protein)
Unknown function(s) FGF-responsive Non/p54nrb
  Unknowns T22, T34, 4-2, 4-4, 4-11, 4-15, 4-20, 4-49, 4-59, BO1
  Unknowns 6-2, 6-3, 6-4, 6-9, 6-10, 6-12