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Figure 2 | Genome Biology

Figure 2

From: The α/β fold uracil DNA glycosylases: a common origin with diverse fates

Figure 2

The topology of the UDG superfamily core fold, with the conserved and unique features of different families. The core secondary-structure elements of the UDG fold are colored as in Figure 1 and numbered according to their order in the sequence. The elements observed only in the MUGs are shown in gray. The conserved motif I occurs after strand 1 and motif II occurs after strand 4 and forms the active-site pocket in the three-dimensional structure.

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