Figure 1

Schematic structure of a retroviral particle. TM, transmembrane components; SU, surface components; IN, integrase; CA, capsid protein; MA, matrix protein; NC, nucleocapsid protein; RT, reverse transcriptase; PR, retroviral protease. Adapted with permission from Retroviruses, Chapter I, by PK Vogt, edited by JM Coffin, SH Hughes and HE Varmus, Cold Spring Harbor Laboratory Press, 1997.