Table 2 Conservation of Tlr4 among six mammalian species, calculated according to region
From: Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (TLR4)
| Â | Human | Chimp | Baboon | Rat | Mouse | Hamster |
|---|---|---|---|---|---|---|
Extracellular domain | Â | Â | Â | Â | Â | Â |
   Human | 100% |  |  |  |  |  |
   Chimp |    99.6% | 100% |  |  |  |  |
   Baboon |    91.5% |    91.5% | 100% |  |  |  |
   Rat |    61.3% |    60.7% |    59.4% | 100% |  |  |
   Mouse |    61.9% |    62.0% |    60.1% |    82.9% | 100% |  |
   Hamster |    64.3% |    64.2% |    62.5% |    73.8% |    74.8% | 100% |
Proximal cytoplasmic domain | Â | Â | Â | Â | Â | Â |
   Human | 100% |  |  |  |  |  |
   Chimp |    99.4% | 100% |  |  |  |  |
   Baboon |    99.4% |    98.7% | 100% |  |  |  |
   Rat |    91.7% |    91.0% |    91.0% | 100% |  |  |
   Mouse |    90.4% |    89.7% |    89.7% |    98.1% | 100% |  |
   Hamster |    91.7% |    91.0% |    91.0% |    97.4% |    95.5% | 100% |
Transmembrane domain | Â | Â | Â | Â | Â | Â |
   Human | 100% |  |  |  |  |  |
   Chimp | 100% | 100% |  |  |  |  |
   Baboon |    97.1% |    97.1% | 100% |  |  |  |
   Rat |    67.7% |    67.7% |    67.7% | 100% |  |  |
   Mouse |    70.6% |    70.6% |    70.6% |    91.2% | 100% |  |
   Hamster |    73.5% |    73.5% |    73.5% |    79.4% |    79.4% | 100% |
Distal cytoplasmic domain | Â | Â | Â | Â | Â | Â |
   Human | 100% |  |  |  |  |  |
   Chimp | 100% | 100% |  |  |  |  |
   Baboon |    50% |    50% | 100% |  |  |  |
   Rat |    38.1% |    38.1% |    ns | 100% |  |  |
   Mouse |    26.3% |    26.3% |    ns |    63.2% | 100% |  |
   Hamster |    40.9% |    40.9% |    ns |    40.96% |    45.5% | 100% |