Fig. 5
From: Enhancing prime editor flexibility with coiled-coil heterodimers
Whole genome sequencing analysis of HEK293T cells treated with sPE-P3P4, PE2 and sPE-ctrl. a-b Bar chart of the number of SNVs (a) and indels (b), data values represent the means, error bars correspond to SE, n = 2, unpaired t-test. c-d Bar chart of the distribution proportion of SNVs (c) and indels (d) on genomic features. e Heat map of the frequency of SNV base substitution. f Density plot of the distribution of indel length. g-h Circos plot of the distribution of SNVs (g) and indels (h) on the genome, color represents mutation density within the 1 × 107 bp windows