Fig. 7
From: spVC for the detection and interpretation of spatial gene expression variation
spVC’s estimation results on the cerebellum spatial transcriptomics data. A Cell type proportions of granule cells, Bergmann cells, oligodendrocytes, Purkinje cells, molecular layer interneurons (MLIs), and astrocytes. B Type I errors of SpatialDE, SPARK, SPARK-X, MERINGUE, and spVC in the permutation analysis. C Number of significant genes whose expression was positively associated with the proportion of each of the six cell types. D Number of significant genes whose expression was negatively associated with the proportion of each of the six cell types. E Relative expression levels of six example genes positively associated with granule cells, Bergmann cells, oligodendrocytes, Purkinje cells, molecular layer interneurons (MLIs), and astrocytes, respectively. The read counts were normalized by library size, log-transformed, and then scaled by the min-max normalization to obtain the relative expression levels