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Fig. 6 | Genome Biology

Fig. 6

From: Multiplex DNA fluorescence in situ hybridization to analyze maternal vs. paternal C. elegans chromosomes

Fig. 6

Homologs frequently intermingle, but rarely align. A The proportion of chromosome pairs (“Density” y axis) is graphed with respect to the degree of territory overlap (% overlap), calculated as the fraction of voxels in the overlap region divided by the total voxels for both territories (x axis). Territory regions were calculated from the N2 and HI probes. N2 and HI chromosomes from crosses between N2m and HIp in different age groups of embryos indicated by color-coding. The % overlap is defined as the ratio between voxels of overlapping N2 and HI marker signal, and total number of voxels defining the N2 territory and HI territory. B Mean spatial distances between all regions of one homolog against all regions of the other homolog for N2 (left) and HI (middle) ChrV in homozygous embryos, colored by distance (in µm). C Mean spatial distances between all regions of one homolog to all regions of the other homolog of HIm and N2p chromosomes (left) and of HIp and N2m (right), colored by distance (in µm). Axis numbering in B and C represents positions across the chromosome as shown in Figure 1C

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