Fig. 4
N2 chromosomes influence HI chromosomes in trans. A ChrV mean distance matrices for traces derived from hybrid embryos (2–40cells) from crosses between HI hermaphrodites and N2 males, HI maternal traces (left), and N2 paternal traces (right), colored by distance (in μm). N = 1125 (HIm) & N = 1254 (N2p). Axis numbering represents positions across the chromosome as shown in Figure 1C. B Power-law fits of mean pairwise distance for N2p data (magenta) and HIm data (green). s = scaling exponent of spatial distance, a = step size. Values in brackets are 95% confidence intervals of the fit. P-values are acquired from a linear regression analysis of log-transformed data. C Normalized mean spatial distances for N2p and HIm traces shown as observed over expected spatial distances as determined by the power-law fit in B. Red denotes regions that are closer together than expected from the fit and blue regions that are further away. D Power-law fits of mean pairwise distance for N2p data (magenta) and N2 homozygous data (black). s = scaling exponent of spatial distance, a = step size. Values in brackets reflect the 95% confidence intervals of the fit. P-values were acquired from a linear regression analysis of log-transformed data. E Differences in normalized mean spatial distances between N2p and HIm traces (left) and p-value (right). Red marks regions that are closer together than expected from the fit and blue regions that are further away. F Power-law fitting of mean pairwise distance for HIm data (green) and HI homozygous data (black). s = scaling exponent of spatial distance, a = step size. Values in brackets are 95% confidence intervals of the fit. P-values are acquired from a linear regression analysis of log-transformed data. G Differences of mean pairwise distances in µm (left), and significant mean changes (right) of N2p and N2 homozygous (top) and HIm and HI homozygous (bottom). Red marks regions that are closer together than expected from the fit and blue regions that are further away. Axis numbering in A, C, E, and G represents positions across the chromosome as shown in Fig. 1C for all panels. Axis numbering represents positions across the chromosome as depicted in Fig. 1C