Fig. 1From: Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicingTypes of models of RNA splicing. a SpliceAI models splicing as a black box mapping from pre-mRNA to splice sites. b We conceptualize splicing as a process in which various protein and ribonucleoprotein factors bind to the pre-mRNA sequence and influence which sites are chosen as splice sites and which are not. c Our SAM model predicts 5′ and 3′ splice site motifs and RBP binding motifs first, and then predicts which splice sites will be chosen by modeling interactions between these motifsBack to article page