Table 1 Trans-ancestry GWAS meta-analysis results (see Additional file 1)

1

I

M + F

rs67807996

1

149,995,265

A

G

0.31

35,014

39

0.067

0.009

1.04E − 12

34,534

5.98E − 11

1.44E − 01

1

OTUD7B

OTUD7B

2

I

M + F

rs823094

1

205,689,807

G

T

0.39

37,407

39

 − 0.038

0.008

1.17E − 06

36,927

2.30E − 08

2.13E − 04

20

RAB7L1

NUCKS1

3

I

F

rs1346789

2

56,092,052

C

T

0.23

23,173

24

 − 0.071

0.011

1.03E − 09

23,173

4.28E − 08

6.35E − 01

11

EFEMP1

EFEMP1, PNPT1

3

I

M + F

rs3791679

2

56,096,892

G

A

0.24

39,411

40

 − 0.068

0.009

7.52E − 15

38,931

1.02E − 12

3.08E − 01

3

 EFEMP1

 EFEMP1, PNPT1

4

I

M + F

rs6763927

3

141,140,366

T

A

0.46

42,928

45

0.049

0.007

4.01E − 12

42,448

4.96E − 10

3.39E − 01

16

RASA2

ZBTB38

5

I

M + F

rs7623981

3

172,135,334

C

T

0.38

40,986

44

 − 0.050

0.008

4.46E − 11

40,506

2.67E − 09

2.17E − 01

6

GHSR

GHSR

6

I

M + F

rs6817306

4

17,868,058

C

T

0.15

39,856

41

 − 0.072

0.011

1.93E − 11

39,376

1.91E − 10

3.79E − 02

6

NCAPG

SLIT2

7

IV

F

rs1712374

4

82,154,710

C

T

0.38

21,200

19

0.082

0.012

9.67E − 11

21,200

4.94E − 09

5.25E − 01

27

PRKG2

PRKG2

7

IV

M + F

rs1443537

4

82,150,880

A

C

0.33

39,039

34

0.073

0.009

1.31E − 14

39,039

4.17E − 12

5.90E − 01

27

 PRKG2

 PRKG2

8

IV

F

rs6537315

4

145,724,712

A

G

0.36

21,645

20

 − 0.066

0.012

1.21E − 07

21,645

4.93E − 08

9.26E − 03

11

HHIP

HHIP

8

I

M + F

rs2131354

4

145,599,908

A

G

0.47

40,541

43

0.044

0.007

4.72E − 09

40,061

2.75E − 08

4.76E − 02

40

 HHIP

 HHIP

9

I

M + F

rs409012

5

77,375,625

C

A

0.22

41,317

43

 − 0.053

0.009

1.60E − 09

40,837

3.98E − 08

1.16E − 01

75

TBCA

AP3B1, OTP

10

IV

M + F

rs2814994

6

34,620,153

A

T

0.17

39,719

35

0.070

0.012

1.65E − 09

39,719

2.79E − 08

1.08E − 01

34

C6orf106 (ILRUN)

C6orf106 (ILRUN)

11

III

M + F

rs2181193

6

105,442,327

A

T

0.67

19,472

26

 − 0.079

0.011

7.81E − 13

19,472

9.59E − 11

4.54E − 11

17

LIN28B

LIN28B

11

V

M + F

rs7766336

6

105,388,405

G

T

0.68

40,667

36

 − 0.006

0.002

0.002158

40,667

6.50E − 10

1.01E − 08

10

 LIN28B

 LIN28B

11

VI

M + F

rs314263

6

105,392,745

T

C

0.69

39,893

36

0.007

0.001

7.25E − 07

39,893

1.93E − 09

4.41E − 05

38

 LIN28B

 LIN28B

12

I

F

rs1159619

6

126,801,144

A

C

0.46

21,466

22

0.063

0.010

4.56E − 10

21,466

2.97E − 09

1.22E − 01

129

CENPW

RSPO3

12

I

M + F

rs1361107

6

126,767,511

C

A

0.46

40,003

42

0.060

0.008

3.05E − 15

39,523

1.64E − 13

8.73E − 02

123

 CENPW

 CENPW

13

I

M + F

rs9496369

6

142,724,918

T

C

0.33

42,928

45

 − 0.052

0.008

2.36E − 11

42,448

2.00E − 09

2.11E − 01

33

ADGRG6

ADGRG6

13

IV

M + F

rs7770386

6

142,775,657

T

C

0.35

39,833

35

 − 0.052

0.009

1.20E − 08

39,833

2.51E − 09

1.65E − 03

14

 ADGRG6

 ADGRG6

14

I

F

rs2167733

8

78,110,734

A

G

0.24

23,618

25

0.073

0.011

3.08E − 11

23,618

2.63E − 09

9.30E − 01

39

PEX2

HNF4G

14

I

M + F

rs10103623

8

78,106,082

G

A

0.24

42,295

45

0.072

0.008

2.87E − 18

41,815

2.30E − 15

6.99E − 01

36

 PEX2

 PEX2

15

III

F

rs72829034

10

64,129,318

A

C

0.08

6660

10

 − 0.005

0.033

8.79E − 01

6660

1.30E − 09

3.05E − 10

1

ZNF365

ARID5B

16

V

M + F

rs16911905

11

5,249,290

C

G

0.10

26,380

21

0.076

0.017

6.84E − 06

26,380

1.32E − 09

4.03E − 06

1

HBB

 HBB

17

I

M + F

rs2724648

12

11,858,191

T

C

0.61

43,373

46

 − 0.049

0.007

1.58E − 11

42,893

6.62E − 09

9.41E − 01

12

ETV6

ETV6

18

VI

M + F

rs2364232

12

93,994,827

C

A

0.25

42,873

40

0.008

0.001

1.20E − 12

42,873

1.65E − 11

7.54E − 02

5

SOCS2

SOCS2

19

I

M + F

rs28481863

12

123,902,361

A

G

0.77

41,317

43

 − 0.054

0.009

1.37E − 09

40,837

4.31E − 08

1.58E − 01

155

KMT5A

 KMT5A

19

IV

M + F

rs28406193

12

123,891,865

G

T

0.74

41,736

38

 − 0.061

0.010

7.43E − 10

41,736

1.14E − 08

9.01E − 02

9

 KMT5A

 KMT5A

20

III

F

rs36103703

14

56,284,991

G

A

0.18

5929

11

 − 0.035

0.025

1.56E − 01

5929

3.82E − 09

2.43E − 09

4

KTN1

KTN1

21

I

M + F

rs11634560

15

67,467,830

G

T

0.25

38,930

41

0.058

0.009

7.58E − 11

38,450

1.98E − 08

9.45E − 01

9

IQCH

SMAD3

22

I

M + F

rs10520573

15

84,591,575

G

A

0.57

41,431

45

0.049

0.007

4.24E − 11

40,951

4.92E − 09

4.69E − 01

69

UBE2Q2L

ADAMTSL3

23

I

M + F

rs71385734

16

2,160,503

G

T

0.20

37,390

38

 − 0.058

0.010

6.72E − 09

36,910

8.60E − 09

8.80E − 03

8

PKD1

PKD1

24

I

F

rs7238093

18

20,728,158

A

T

0.20

21,683

23

 − 0.081

0.012

5.58E − 11

21,683

4.04E − 09

8.60E − 01

15

CABLES1

 CABLES1

24

IV

F

rs8094261

18

20,746,728

C

G

0.78

21,645

20

0.095

0.014

5.46E − 11

21,645

4.89E − 09

7.89E − 01

13

 CABLES1

 CABLES1

24

I

M + F

rs7244464

18

20,729,714

C

A

0.77

42,601

46

0.075

0.009

2.16E − 18

42,121

3.70E − 15

8.67E − 01

12

 CABLES1

 CABLES1

24

IV

M + F

rs7238093

18

20,728,158

T

A

0.80

42,740

40

0.081

0.011

3.45E − 14

42,740

9.07E − 12

5.14E − 01

13

 CABLES1

 CABLES1

25

I

M

rs143384

20

34,025,756

G

A

0.44

19,755

21

0.063

0.011

5.35E − 08

19,755

1.22E − 08

5.65E − 03

59

GDF5

GDF5

25

I

M + F

rs143384

20

34,025,756

G

A

0.45

41,711

44

0.060

0.008

2.14E − 15

41,231

1.12E − 13

7.34E − 02

1

 GDF5

 GDF5

25

IV

M + F

rs143384

20

34,025,756

G

A

0.49

41,850

38

0.063

0.009

5.81E − 12

41,850

4.06E − 10

2.40E − 01

67

 GDF5

 GDF5

26

I

M + F

rs1326022

20

54,844,025

G

A

0.69

37,469

39

 − 0.053

0.008

4.61E − 10

36,989

4.25E − 09

4.83E − 02

19

MC3R

MC3R