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Fig. 3 | Genome Biology

Fig. 3

From: Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate

Fig. 3

Integrated analysis of the transcriptome and proteome response of P. cordatum to heat stress. a Experimental design. b Growth of P. cordatum at 20, 26, and 30°C. Collection of cells for multi-omics analysis is indicated by dashed vertical lines (Ex: exponential, St: stationary phase). c Ternary plots of highly expressed gene models with mean log2(count per million) > 5 in response to temperature and growth phase (8593 transcripts in each plot). d Clustering of 2098 differentially abundant proteins in response to temperature and growth phase. Abundances of proteins were calculated from standardized peptide counts. e Heatmap of transcripts and proteins showing significant correlations for generalized heat stress response (component 1) and temperature-specific response (component 2). f Over-represented KEGG pathways in the networks of generalized and temperature-specific heat stress response. g DIABLO network of generalized heat stress response (component 1) revealing positive and negative correlations (coefficient ≥ 0.7) between transcripts and proteins

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