Fig. 1
From: ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model
Overview of the ConDoR algorithm. ConDoR takes as input: a a clustering of cells based on copy-number profiles and b the observed variant and total read counts from scDNA-seq data. ConDoR employs the constrained k-Dollo model to construct the c constrained k-Dollo phylogeny with mutation losses (dashed box) allowed only between cells from distinct copy-number clusters and the d inferred mutation matrix