Fig. 7

Boxplots of total RNA nuclear expression in the nucleus across cell types. a Distribution of total nuclear RNA expression (estimated with the sum of total UMIs per nucleus) in DLPFC snRNA-seq data across excitatory neurons (Excit), inhibitory neurons (Inhib), and oligodendrocytes (Oligo). b Distribution of the number of puncta quantified by RNAscope for each observed gene across the same cell types as in a. The number of puncta by RNAscope estimates the total RNA expression by snRNA-seq (Fig. 1a). POLR2A was only evaluated in excitatory neurons and oligodendrocytes as it was multiplexed with MALAT1 and GAD1 was omitted