Fig. 6

Quantification of candidate TREG AKT3 in differently sized cell types in human DLPFC. Representative tissue section showing a raw fluorescence for nuclear DAPI signals and a’ corresponding mean nuclear area size. The nuclear area based on the DAPI signal shows larger excitatory neuron nuclei in gray matter from smaller glial nuclei in the white matter, related to Fig. 4b. b Raw fluorescence for DAPI and AKT3 and b’ corresponding quantification of the mean number of AKT3 puncta per nucleus. c Raw fluorescence for DAPI and one of the following (SLC17A7, GAD1, and MBP) compared to c’ the quantified distribution of the number of SLC17A7 + excitatory neurons (Excit), GAD1 + inhibitory neurons (Inhib), and MBP + oligodendrocytes (Oligo), respectively. Scale bar in a for a–c is 1 mm