Table 2 Metrics information summary
Metric | Category | Input type | Package Version | Reference |
|---|---|---|---|---|
MAD | Generic | Normalized | stats version 4.1.1 | - |
SD | Generic | Normalized | stats version 4.1.1 | - |
IQR | Generic | Normalized | stats version 4.1.1 | - |
Coefficient of variation | Generic | Normalized | scVar version 1.0.0 | |
Fano Factor | Generic | Normalized | scVar version 1.0.0 | |
Local coefficient of variation | Local normalization | Normalized | scVar version 1.0.0 | [55] |
DESeq2 | Regression-model based | Raw | DESeq2 version 1.32.0 | [56] |
Distance to median (DM) | Regression-model based | Raw | scVar version 1.0.0 | |
edgeR | Regression-model based | Raw | edgeR version 3.34.1 | [57] |
glmGamPoi | Regression-model based | Raw | glmGamPoi version 1.4.0 | [58] |
scran | Regression-model based | Raw | scran version 1.20.1 | [59] |
Seurat_mvp | Regression-model based | Raw | Seurat version 4.3.0 | |
Seurat_vst | Regression-model based | Raw | Seurat version 4.3.0 | |
BASiCS | Bayesian modeling | Raw | BASiCS version 2.4.0 | [62] |