Fig. 2

RNA expression level as a proxy for protein translation and MAP generation. a The abundance of 3586 proteins (assessed in [30]) was correlated to their corresponding transcript abundance (obtained with Kallisto from public TCGA RNA-seq data) across 115 high-grade serous ovarian cancer patients for which matched proteomic and transcriptomic data were available. Left panel: representative correlation obtained for the TP53BP1 gene across 115 patients. Right panel: distribution of the frequency of genes (n = 3586) and p-values among different categories of correlation values (r), incremented by 0.05 from − 0.25 to + 0.9. b Transcription expression level distribution of MAP source and non-source genes in three DLBCL cell lines. c Correlation between BamQuery RNA expression and BamQuery Ribo-seq expression (in RPHM) of 6833 MAPs detected in 3 DLBCL cell lines